The Greek word anaideia in Luke 11:18 is translated as “boldness” or “persistence”, but it literally means “shamelessness”, “cheek” or “nerve”.
We need the boldness and determination to think, “I need this provision, and I will not be put off by anything until I have obtained it”.
We need holy audacity – based on the strenght of our relationship with God, the confident knowledge of his will and the assurance that we are welcomed into his presence – to ask him with nerve and check.
We need the audacity to ask God for big things – as in Psalm 2:8. We should not be intimidated or limited by the suggestions of the enemy in how often we approach God’s throne, or what we ask when get there”. (From Colin Dye, Effective Prayer, London 2007)